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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCQ
All Species:
52.12
Human Site:
Y545
Identified Species:
76.44
UniProt:
Q04759
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04759
NP_006248.1
706
81865
Y545
T
F
C
G
T
P
D
Y
I
A
P
E
I
L
L
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
Y545
T
F
C
G
T
P
D
Y
I
A
P
E
I
L
L
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
Y978
T
F
C
G
T
P
D
Y
I
A
P
E
I
L
Q
Dog
Lupus familis
XP_849292
706
81555
Y545
T
F
C
G
T
P
D
Y
I
A
P
E
I
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q02111
707
81555
Y545
T
F
C
G
T
P
D
Y
I
A
P
E
I
L
L
Rat
Rattus norvegicus
Q9WTQ0
707
81732
Y545
T
F
C
G
T
P
D
Y
I
A
P
E
I
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
Y547
T
F
C
G
T
P
D
Y
I
A
P
E
I
L
L
Chicken
Gallus gallus
NP_001006133
699
80179
Y537
T
F
C
G
T
P
D
Y
I
A
P
E
I
L
Q
Frog
Xenopus laevis
Q7LZQ8
671
76506
Y504
T
F
C
G
T
P
D
Y
I
A
P
G
I
I
R
Zebra Danio
Brachydanio rerio
Q7SY24
670
76288
Y504
T
F
C
G
T
P
D
Y
I
A
P
E
I
I
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
Y468
T
F
C
G
T
P
D
Y
I
A
P
E
I
L
K
Honey Bee
Apis mellifera
XP_394743
624
71014
Y467
T
F
C
G
T
P
D
Y
M
A
P
E
I
I
K
Nematode Worm
Caenorhab. elegans
P34722
704
80280
Y541
T
F
C
G
T
P
D
Y
I
S
P
E
I
I
K
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
Q467
F
H
G
E
D
E
D
Q
L
F
D
C
I
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
F990
T
F
C
G
T
P
E
F
M
A
P
E
I
L
K
Red Bread Mold
Neurospora crassa
P87253
1142
127954
F983
T
F
C
G
T
P
E
F
M
A
P
E
I
L
L
Conservation
Percent
Protein Identity:
100
99.7
33.6
96.7
N.A.
94.7
94
N.A.
86.1
63.3
33.9
34.1
N.A.
42.9
43.2
47.1
47.8
Protein Similarity:
100
99.7
45.1
98.3
N.A.
97.5
96.8
N.A.
92.9
77.1
48.2
49.2
N.A.
58.7
58.9
64.1
62
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
100
93.3
80
86.6
N.A.
93.3
80
80
20
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
100
93.3
86.6
93.3
N.A.
93.3
93.3
93.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.2
26.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.3
40.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
73.3
80
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
93.3
100
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
88
0
0
0
0
7
% A
% Cys:
0
0
94
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
0
0
0
7
0
88
0
0
0
7
0
0
0
0
% D
% Glu:
0
0
0
7
0
7
13
0
0
0
0
88
0
0
0
% E
% Phe:
7
94
0
0
0
0
0
13
0
7
0
0
0
0
0
% F
% Gly:
0
0
7
94
0
0
0
0
0
0
0
7
0
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
0
0
75
0
0
0
100
25
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% K
% Leu:
0
0
0
0
0
0
0
0
7
0
0
0
0
75
44
% L
% Met:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
94
0
0
0
0
94
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
13
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% R
% Ser:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% S
% Thr:
94
0
0
0
94
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _